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Prototype · Illustrative synthetic data · Not real patient or company data

Patient Pathway & Transition

Level 2 · Brand & Patient Services

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Launch phaseView as
Synthetic snapshot Launch Week 14 · Claims held W13
Viewing as Brand lead · Level 1 · Governance read-only

The seven-stage pathway from HCP engagement to business value: barrier, core KPI and data sources per stage, plus who needs action this week.

Seven-stage pathway

Each stage: barrier · core KPI · primary data sources. EAP/trial transition runs alongside all stages and is reported separately.

  1. 1HCP engagement
    Barrier: Awareness and engagement gap
    Core KPI: Priority-account pathway adoption
    Priority-account pathway adoption: 63%
    CRM, EHR, claims
  2. 2Referral & evaluation
    Barrier: Referral breakdown and capacity constraint
    Core KPI: Treatment-decision completion (30 days)
    Treatment-decision completion (30 days): 82%
    Hub, EHR
  3. 3FUS confirmation
    Barrier: Testing variability
    Core KPI: New qualifying FUS+ patients
    New qualifying FUS+ patients: 64
    Genetic testing (partner TBC), EHR
  4. 4Treatment readiness
    Barrier: Decision and coordination gap
    Core KPI: Treatment-center readiness
    Treatment-center readiness: 77%
    Center readiness checklist, SD 867
  5. 5Access pull-through
    Barrier: Coverage and delivery barrier
    Core KPI: Final denial rate · submission → approval · decision → first dose
    Final denial rate: 8%
    Avg days submission → approval: 9.4 days
    Median days decision → first dose: 26 days
    Hub, claims · sub-steps: hub enrolled → benefits verified → coverage approved
  6. 6Treatment continuity
    Barrier: Logistics and continuity gap
    Core KPI: Month-6 persistence
    Not yet evaluable — first month-6 cohort matures around W26
    SD 867, claims, hub
  7. 7Business value
    Barrier: Performance gap by US region
    Core KPI: Patient starts + sales attainment (% of forecast)
    Active patients on commercial ulefnersen: 47
    Sales attainment (% of forecast): 92%
    SD 867, hub, internal sales

Stage flow

Stages 2–6 · cumulative patients reaching each step (hub, benefits and coverage are access sub-steps) · excludes EAP/trial transitions

Funnel ends at 29 active new starts, excluding transitions. Total active commercial: 47. See Patient bridge.

Time in current stage

Days · IQR bar, median tick, dashed threshold

Evaluatedmedian 9d · threshold 14d
FUS+ confirmedmedian 12d · threshold 14d
Decision at ready centermedian 28d · threshold 30d
Hub enrolledmedian 5d · threshold 7d
Benefits verifiedmedian 18d · threshold 14d
Coverage approvedmedian 17d · threshold 14d
New startsmedian 86d · threshold 30d

Stalled patients · aggregates

Current-stage attention · aggregate-only view

Referred and evaluated3 stalled
FUS+ confirmed (P/LP)4 stalled
Treatment decision at a ready center3 stalled
Hub enrolled0 stalled
Benefits verified5 stalled
Coverage approved6 stalled
New commercial starts2 stalled
Active on therapy (new starts)0 stalled

EAP & trial transition tracker

22 eligible · 18 transitioned · 3 in progress · 1 gap in therapy; transitions are additional to active new starts

18
Transitioned
3
In progress
1
Gap in therapy

Patient bridge

Total active commercial: 47 · 29 new starts · 18 transitioned from EAP/trials

Certified KPI
3 transitions in progress · 1 gap in therapy (alert)